Translational Nanomedicine and Drug Delivery
Translational Nanomedicine and Drug Delivery (TNDD) is designed for students who are interested in molecular design of nanomedicine platforms to help translate basic biological science to clinical medicine. TNDD is ideally suited for students with strong engineering, physical science, or biology background and a keen desire to cross the boundaries between traditional scientific disciplines.
Research Topics
TNDD faculty members are from a diverse scientific, engineering, and clinical background to offer a highly interdisciplinary training environment. Molecular design and nano engineering are closely integrated with pathophysiology and biology rationales to establish emerging precision paradigms for disease diagnosis and therapy. Examples include:
- Nano delineation of tumor boundaries for image-guided cancer surgery
- Minimalist nanovaccine for immunotherapy
- Theranostic nanomedicine integrating imaging and therapeutic delivery targeting diabetes or cancer
- Cancer-targeted siRNA/miRNA delivery and therapy
Faculty
Professor
Research Interests: Molecular Imaging; optical imaging; instrument development; image-guided surgery; cancer treatment, molecular probes; spectroscopy, multimodal nuclear and magnetic imaging; stimulated thermal imaging, nanomedicine
Associate Professor
Research Interests: Drug resistance mechanism, drug delivery systems, nanoparticles, immunotherapy, tissue engineering
Professor
Research Interests: Activatable optical/MRI imaging probes to study tumor metabolism and theranostic nanomedicine for cancer-targeted drug therapy
Assistant Professor
Research Interests: Ultrasound contrast agent, perfluorocarbon emulsions, development of new ultrasound-based strategies for early detection and treatment of diseases
Associate Professor
Research Interests: Ultrasound-guided drug and gene delivery, Targeted drug delivery system, Materials Science, Immunotherapy, Image-guided therapy, Nanomedicine
Professor
Research Interests: Nanomedicine, immunotherapy, ultrasound and radiation guided chemo-immunonotherapy
Professor
Research Interests: Polymer and materials chemistry, drug and gene delivery, RNAi, biomedical imaging, detection and treatment of cancer
Professor
Research Interests: Clinical application of nanoprobes with unique nanoscale behavior
Professor
Research Interests: Development of PET, SPECT, and MRI imaging probes to assess biological abnormalities and evaluation of disease treatment
Assistant Professor
Research Interests: Biomaterials, immunoengineering, infection tissue engineering
Associate Members
These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program activities.
Assistant Professor
Research Interests: Evolution of molecular components of the nervous system, gene therapy for genetic disorders, how pain alters cognitive function and leads to co-morbid addiction, how pain is altered by cognitive state
Assistant Professor
Research Interests: Nanomedicine, lipid nanoparticles, mRNA, siRNA, CRISPR/Cas, base editing, genetic medicines, gene editing
Somesree GhoshMitra, M.D., Ph.D.
Assistant Professor
Research Interests: Nanomaterials, cancer research, axon regeneration
Professor
Research Interests: Cervical cancer, developmental therapeutics, ovarian cancer, early detection of ovarian cancer
Assistant Professor
Research Interests: Pathogen inactivation, cancer prevention, aging research
Professor
Research Interests: Application of biomedical engineering to cancer research, developing novel cancer diagnostics and therapeutics to improve cancer treatment, genitourinary cancer, gastrointestinal cancers, biomedical engineering, nanotechnology, radiation oncology, translational research, cancer immunotherapy, cancer nanotherapeutics, cancer biomarkers, radioisotopes, nanoparticles, prostate cancer, chemoradiotherapy